High tumour islet macrophage infiltration correlates with improved patient survival but not with EGFR mutations, gene copy number or protein expression in resected non-small cell lung cancer.

doi:10.1038/sj.bjc.6604256

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High tumour islet macrophage infiltration correlates with improved patient survival but not with EGFR mutations, gene copy number or protein expression in resected non-small cell lung cancer.

British journal of cancer - 25 Mar 2008

Kim D-W, Min H S, Lee K-H, Kim Y J, Oh D-Y, Jeon Y K, Lee S-H, Im S-A, Chung D H, Kim Y T, Kim T-Y, Bang Y-J, Sung S W, Kim J H, Heo D S

Abstract excerpt

The purpose of this study was to investigate the prognostic value of tumour-associated macrophages with a focus on micro-anatomical localisation and determine whether molecular changes of the epidermal growth factor receptor (EGFR) are related to macrophage infiltration in resected non-small cell lung cancer (NSCLC). One hundred and forty-four patients were included in this study. Immunohistochemistry was used to...

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High tumour islet macrophage infiltration correlates with improved patient survival but not with EGFR mutations, gene copy number or protein expression in resected non-small cell lung cancer.

Abstract excerpt

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