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Article

Clinicopathological and Prognostic Significance of the EML4-ALK Translocation and IGFR1, TTF1, Napsin A Expression in Patients with Lung Adenocarcinoma.

Turk patoloji dergisi - 1 Jan 2021

Bulutay Pınar, AkyÜrek Nalan, MemiŞ Leyla

Abstract excerpt

OBJECTIVE: Patients with lung adenocarcinoma who harbor ALK gene rearrangements can demonstrate significant clinical benefit with ALK tyrosine kinase inhibitors. Insulin-like growth factor receptor 1 (IGFR1) is a cellular membrane receptor that is overexpressed in many tumors. It plays an important role in cancer progression and is associated with increased postoperative recurrence and poorer disease-free...

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Share to Adenocarcinoma of Lung
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Fusion

Share to Immunohistochemistry

Share to In Situ Hybridization, Fluorescence

Share to Oncogene Proteins, Fusion

Share to Receptor, IGF Type 1

Share to Translocation, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 32876329
DOI: 10.5146/tjpath.2020.01503
PMCID: PMC10508933

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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