Article
Clinical outcome according to the level of preexisting epidermal growth factor receptor T790M mutation in patients with lung cancer harboring sensitive epidermal growth factor receptor mutations.
Cancer - 15 Jul 2014
Lee Youngjoo, Lee Geon Kook, Lee Yeon-Su, Zhang Wenji, Hwang Jung-Ah, Nam Byung-Ho, Kim Seok Hyun, Kim Joo-Hang, Yun Tak, Han Ji-Youn, Kim Heung Tae, Lee Jin Soo
Abstract excerpt
BACKGROUND: Epidermal growth factor receptor (EGFR) T790M mutation drives acquired drug resistance to EGFR tyrosine kinase inhibitors (EGFR-TKIs) in patients with EGFR-mutant lung cancer. However, it was reported that this mutation may exist before drug exposure. The objective of the current stud...
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