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Article

Clinical implications of T790M mutation in patients with acquired resistance to EGFR tyrosine kinase inhibitors.

Lung cancer (Amsterdam, Netherlands) - 1 Nov 2013

Sun Jong-Mu, Ahn Myung-Ju, Choi Yoon-La, Ahn Jin Seok, Park Keunchil

Abstract excerpt

OBJECTIVES: Although T790M mutation is considered to be the major mechanism of acquired resistance to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) in patients with non-small cell lung cancer (NSCLC), its clinical implication remains undetermined. METHODS: Post-progression tumor specimens were prospectively collected for T790M mutation analysis in NSCLC patients with acquired...

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Source

Identifiers

PMID: 24035188
DOI: 10.1016/j.lungcan.2013.08.023

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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