Article
Prognostic impact of pretreatment T790M mutation on outcomes for patients with resected, EGFR-mutated, non-small cell lung cancer.
BMC cancer - 15 Jul 2022
Matsumoto Yoshiya, Kawaguchi Tomoya, Watanabe Masaru, Isa Shun-Ichi, Ando Masahiko, Tamiya Akihiro, Kubo Akihito, Kitagawa Chiyoe, Yoshimoto Naoki, Koh Yasuhiro
Abstract excerpt
BACKGROUND: Many previous studies have demonstrated that minor-frequency pretreatment T790M mutation (preT790M) could be detected by ultrasensitive methods in a considerable number of treatment-naïve, epidermal growth factor receptor (EGFR)-mutated, non-small cell lung cancer (NSCLC) cases. However, the impact of preT790M in resected cases on prognosis remains unclear. METHODS: We previously reported that...
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