Article
High resolution systematic digital histological quantification of cardiac fibrosis and adipose tissue in phospholamban p.Arg14del mutation associated cardiomyopathy.
PloS one - 1 Jan 2014
Gho Johannes M I H, van Es René, Stathonikos Nikolas, Harakalova Magdalena, te Rijdt Wouter P, Suurmeijer Albert J H, van der Heijden Jeroen F, de Jonge Nicolaas, Chamuleau Steven A J, de Weger Roel A, Asselbergs Folkert W, Vink Aryan
Abstract excerpt
Myocardial fibrosis can lead to heart failure and act as a substrate for cardiac arrhythmias. In dilated cardiomyopathy diffuse interstitial reactive fibrosis can be observed, whereas arrhythmogenic cardiomyopathy is characterized by fibrofatty replacement in predominantly the right ventricle. Th...
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