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Article

The KRAS-variant and miRNA expression in RTOG endometrial cancer clinical trials 9708 and 9905.

PloS one - 1 Jan 2014

Lee Larissa J, Ratner Elena, Uduman Mohamed, Winter Kathryn, Boeke Marta, Greven Kathryn M, King Stephanie, Burke Thomas W, Underhill Kelly, Kim Harold, Boulware Raleigh J, Yu Herbert, Parkash Vinita, Lu Lingeng, Gaffney David, Dicker Adam P, Weidhaas Joanne

Abstract excerpt

OBJECTIVE: To explore the association of a functional germline variant in the 3'-UTR of KRAS with endometrial cancer risk, as well as the association of microRNA (miRNA) signatures and the KRAS-variant with clinical characteristics and survival outcomes in two prospective RTOG endometrial cancer trials. METHODS/MATERIALS: The association of the KRAS-variant with endometrial cancer risk was evaluated by...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Neoplastic

Share to Lymphatic Metastasis

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Share to Proto-Oncogene Proteins

Share to Proto-Oncogene Proteins p21(ras)

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Source

Open in PubMed Open full text

Identifiers

PMID: 24732316
DOI: 10.1371/journal.pone.0094167
PMCID: PMC3986055

Genes

KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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