Article
MIRSNP rs2910164 of miR-146a is associated with the muscle involvement in polymyositis/dermatomyositis.
International journal of dermatology - 1 Mar 2014
Okada Yoshifumi, Jinnin Masatoshi, Makino Takamitsu, Kajihara Ikko, Makino Katsunari, Honda Noritoshi, Nakayama Wakana, Inoue Kuniko, Fukushima Satoshi, Ihn Hironobu
Abstract excerpt
BACKGROUND: Recently, single nucleotide polymorphisms (SNPs) located in microRNAs, the so-called MIRSNPs, have attracted attention for their possible involvement in the pathogenesis of various diseases. Such MIRSNPs may have a functional role, due to the alteration of microRNA function, and can be a disease marker. In this study, we evaluated the possibility that MIRSNP rs2910164 in miR-146a can be a useful...
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