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Article

Overexpression of microRNA-206 in the skeletal muscle from myotonic dystrophy type 1 patients

20 May 2010

Abstract excerpt

BACKGROUND: MicroRNAs are highly conserved, noncoding RNAs involved in post-transcriptional gene silencing. They have been shown to participate in a wide range of biological processes, including myogenesis and muscle regeneration. The goal of this study is to test the hypothesis that myo-miRs (myo = muscle + miR = miRNA) expression is altered in muscle from patients affected by myotonic dystrophy type 1 (DM1),...

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PMID: 20487562
DOI: 10.1186/1479-5876-8-48

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