Article
Polymorphism in the ADRB2 gene explains a small portion of intersubject variability in pain relative to cervical dilation in the first stage of labor.
Anesthesiology - 1 Jul 2014
Terkawi Abdullah S, Jackson William M, Hansoti Shehnaz, Tabassum Rabeena, Flood Pamela
Abstract excerpt
BACKGROUND: Variability in labor pain has been associated with demographic, clinical, and psychological factors. Polymorphisms of the β2-adrenergic receptor gene (ADRB2) influence sensitivity to experimental pain in humans and are a risk factor for chronic pain. The authors hypothesized that polymorphisms in ADRB2 may influence labor pain. METHODS: After Institutional Review Board approval and written informed...
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