Article
Common fibroid-associated genes are differentially expressed in phenotypically dissimilar cell populations isolated from within human fibroids and myometrium.
Reproduction (Cambridge, England) - 1 May 2014
Holdsworth-Carson Sarah J, Zaitseva Marina, Girling Jane E, Vollenhoven Beverley J, Rogers Peter A W
Abstract excerpt
Uterine fibroids are a prevalent gynaecological condition in reproductive-aged women and are the commonest reason for hysterectomy. The cellular composition of clonal fibroids are heterogeneous, with phenotypically dissimilar cells that include smooth muscle cells (SMC), vascular SMC (VSMC) and fibroblasts. The aim of our study was to investigate genes that are commonly differentially expressed between fibroid...
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