Article
Variations in mitochondrial tRNA(Thr) gene may not be associated with coronary heart disease.
Mitochondrial DNA. Part A, DNA mapping, sequencing, and analysis - 1 Jan 2016
Pei Hui, Peng Qian, Lan Chao, Liu Bao Chi
Abstract excerpt
Mutations in mitochondrial tRNAThr gene were recently reported to be associated with coronary heart disease. These mutations, such as T15889C, G15927A, G15930A and A15951G, were claimed to be pathogenic. To examine whether these mutations contributed to the genetic susceptibility to coronary heart disease, we analyzed the conservation index of these mutations between different species. In particular, reports...
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