Article
Familial Mediterranean fever gene mutations as a risk factor for early coronary artery disease.
International journal of rheumatic diseases - 1 Dec 2017
Basar Nurcan, Kisacik Bunyamin, Ercan Suleyman, Pehlivan Yavuz, Yilmaz Sedat, Simsek Ismail, Erdem Hakan, Ozer Orhan, Pay Salih, Onat Ahmet M, Dinc Ayhan
Abstract excerpt
OBJECTIVE: Cardiovascular diseases (CVD) are very common in the general population. Atherosclerosis is the main pathogenesis. Familial Mediterranean fever (FMF) is an autosomal recessive disease. The gene causing FMF, designated MEFV, encodes a protein called pyrin or marenostrin that is expressed mainly in myeloid bone marrow precursors, neutrophils and monocytes. We herein aimed to determine the prevalence of...
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