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Mediterranean fever (MEFV) gene mutation frequency is not increased in adults with rheumatic heart disease.

Clinical rheumatology - 1 Apr 2011

Simsek Ismail, Koz Cem, Basar Nurcan, Sari Ismail, Erdem Hakan, Pay Salih, Kisacik Bunyamin, Bahce Muhterem, Dinc Ayhan

Abstract excerpt

It is well established that there are people with higher risk of developing acute rheumatic fever (ARF) and rheumatic heart disease (RHD). Mediterranean fever (MEFV) gene mutations might be one of the genetic predisposition factors in the development of ARF/RHD since defect in familial Mediterranean fever (FMF) patients is proposed to be heightened inflammatory response to certain stimuli. Previous clinical...

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Familial Mediterranean Fever
Prevalence
Cytoskeletal Proteins
DNA Mutational Analysis
Pyrin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Rheumatic Heart Disease

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Identifiers

PMID: 20645115
DOI: 10.1007/s10067-010-1537-9

Genes

RHD
MEFV

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Mediterranean fever (MEFV) gene mutation frequency is not increased in adults with rheumatic heart disease.PMID 20645115Read ↗

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