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Article

Mass spectrometry-based comparative sequence analysis for the genetic monitoring of influenza A(H1N1)pdm09 virus.

PloS one - 1 Jan 2014

Gooskens Jairo, Zevenhoven-Dobbe Jessika C, Claas Eric C, Kroes Aloys C M, Posthuma Clara C

Abstract excerpt

The pandemic influenza A (H1N1) 2009 virus (pH1N1) contains novel gene segments of zoonotic origin that lack virulence and antiviral resistance markers. We aimed to evaluate the applicability and accuracy of mass spectrometry-based comparative sequence analysis (MSCSA) to detect genetic mutations associated with increased virulence or antiviral resistance in pH1N1. During the 2009 H1N1 pandemic, routine...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Neuraminidase

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Share to Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

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Source

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Identifiers

PMID: 24699508
DOI: 10.1371/journal.pone.0092970
PMCID: PMC3974683

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