Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Trefoil factors in inflammatory bowel disease.

World journal of gastroenterology - 28 Mar 2014

Aamann Luise, Vestergaard Else Marie, Grønbæk Henning

Abstract excerpt

Inflammatory bowel disease (IBD), which comprises ulcerative colitis and Crohn's disease, is characterized by inflammation of the gastrointestinal tract. The trefoil factors 1, 2, and 3 (TFF1-3) are a family of peptides that play important roles in the protection and repair of epithelial surfaces, including the gastrointestinal tract. TFFs may be involved in IBD pathogenesis and are a potential treatment option....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apoptosis
Share to Biomarkers
Share to Colitis, Ulcerative

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Crohn Disease

Share to Inflammation

Share to Inflammatory Bowel Diseases

Share to Peptides

Share to Tumor Suppressor Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 24696606
DOI: 10.3748/wjg.v20.i12.3223
PMCID: PMC3964394

Genes

TFF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Trefoil factors in inflammatory bowel disease.PMID 24696606Read ↗

Serum Human Trefoil Factor 3 is a Biomarker for Mucosal Healing in Ulcerative Colitis Patients with Minimal Disease ActivitySemantic proximity Read ↗

The Gene Encoding Human Intestinal Trefoil Factor (TFF3) Is Located on Chromosome 21q22.3 Clustered with Other Members of the Trefoil Peptide FamilySemantic proximity Read ↗

Trefoil Factor Family (TFF) Peptides and their Different Roles in the Mucosal Innate Immune Defense and More: An UpdateSemantic proximity Read ↗

Down-regulation of <i>TFF</i> Expression in Gastrointestinal Cell Lines by Cytokines and Nuclear FactorsSemantic proximity Read ↗

Growth Factors in Inflammatory Bowel DiseaseSemantic proximity Read ↗

Colitis-associated variant of TLR2 causes impaired mucosal repair because of TFF3 deficiency.Semantic proximity Read ↗

LINGO3 interacts with Trefoil factor 2 to enforce mucosal barrier integrity and drive tissue repair during colitisSemantic proximity Read ↗

Tissue Localization of Human Trefoil Factors 1, 2, and 3Semantic proximity Read ↗

The Role of TGF-β, Activin and Follistatin in Inflammatory Bowel DiseaseSemantic proximity Read ↗

Matrix metalloproteinases in inflammatory bowel disease: an update.Semantic proximity Read ↗

LINGO3 regulates mucosal tissue regeneration and promotes TFF2 dependent recovery from colitisSemantic proximity Read ↗

Alterations in the Composition of the Supramucosal Defense Barrier in Relation to Disease Severity of Ulcerative ColitisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.