Article
Matrix metalloproteinases in inflammatory bowel disease: an update.
Mediators of inflammation - 1 Jan 2015
O'Sullivan Shane, Gilmer John F, Medina Carlos
Abstract excerpt
Matrix metalloproteinases (MMPs) are known to be upregulated in inflammatory bowel disease (IBD) and other inflammatory conditions, but while their involvement is clear, their role in many settings has yet to be determined. Studies of the involvement of MMPs in IBD since 2006 have revealed an array of immune and stromal cells which release the proteases in response to inflammatory cytokines and growth factors....
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