Article
CTCF regulates the human p53 gene through direct interaction with its natural antisense transcript, Wrap53.
Genes & development - 1 Apr 2014
Saldaña-Meyer Ricardo, González-Buendía Edgar, Guerrero Georgina, Narendra Varun, Bonasio Roberto, Recillas-Targa Félix, Reinberg Danny
Abstract excerpt
The multifunctional CCCTC-binding factor (CTCF) protein exhibits a broad range of functions, including that of insulator and higher-order chromatin organizer. We found that CTCF comprises a previously unrecognized region that is necessary and sufficient to bind RNA (RNA-binding region [RBR]) and...
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