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Article

Functional CYP2B6 variants and virologic response to an efavirenz-containing regimen in Port-au-Prince, Haiti.

The Journal of antimicrobial chemotherapy - 1 Aug 2014

Haas David W, Severe Patrice, Jean Juste Marc Antoine, Pape Jean William, Fitzgerald Daniel W

Abstract excerpt

OBJECTIVES: Efavirenz is widely prescribed for HIV-1 infection. Three polymorphisms in CYP2B6 define plasma efavirenz trough concentration strata that vary across an ∼10-fold range. We characterized associations between human genetic polymorphisms and virologic response among participants who rec...

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Identifiers

PMID: 24695352
DOI: 10.1093/jac/dku088
PMCID: PMC4100704

Genes

ABCB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24695352-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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