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Article

Impact of EZH2 polymorphisms on urothelial cell carcinoma susceptibility and clinicopathologic features.

PloS one - 1 Jan 2014

Yu Yung-Luen, Su Kuo-Jung, Hsieh Ming-Ju, Wang Shian-Shiang, Wang Po-Hui, Weng Wei-Chun, Yang Shun-Fa

Abstract excerpt

BACKGROUND: The gene EZH2, the polycomb group protein enhancer of zeste 2, encodes a transcriptional repressor that also serves as a histone methyltransferase that is associated with progression to more advanced disease in a variety of malignancies. EZH2 expression level in urothelial cell carcinoma (UCC) is highly correlated with tumor aggressiveness, but it has not been determined if specific EZH2 genetic...

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Identifiers

PMID: 24691023
DOI: 10.1371/journal.pone.0093635
PMCID: PMC3972169

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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