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Article

Genetic polymorphisms in the polycomb group gene EZH2 and the risk of lung cancer.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Jan 2010

Yoon Kyong-Ah, Gil Hye Jin, Han Jihye, Park Jaehee, Lee Jin Soo

Abstract excerpt

INTRODUCTION: Polycomb group (PcG) proteins play essential roles in cellular memory systems and as cell cycle regulators by maintaining homeotic genes in their silenced states. EZH1 and EZH2, the human homologues of the Drosophila gene Enhancer of Zeste (E(z)), are defined as PcG proteins and contain a highly conserved motif, called the SET (Su(var)3-9, Enhancer of Zeste, Trithorax) domain, which is required for...

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Identifiers

PMID: 19901851
DOI: 10.1097/JTO.0b013e3181c422d9

Genes

SET

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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