Article
An A/G polymorphism rs3746444 in miR-499 is associated with increased cancer risk: a meta-analysis.
Genetics and molecular research : GMR - 23 Sept 2013
Wang N, Tian Z Q, Li Y, Zhou R M, Wang G Y
Abstract excerpt
An A/G polymorphism (rs3746444) has been identified in the miR-499 gene that can change the conformation of the secondary gene structure and thereby directly affect binding to target mRNAs and the microRNA (miRNA) maturation process, thus altering protein expression and potentially contributing to cancer susceptibility. Numerous studies investigating the association between the rs3746444 polymorphism and cancers...
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