Article
Finding alternative expression quantitative trait loci by exploring sparse model space.
Journal of computational biology : a journal of computational molecular cell biology - 1 May 2014
Wang Zhiyong, Xu Jinbo, Shi Xinghua
Abstract excerpt
Sparse modeling, a feature selection method widely used in the machine-learning community, has been recently applied to identify associations in genetic studies including expression quantitative trait locus (eQTL) mapping. These genetic studies usually involve high dimensional data where the number of features is much larger than the number of samples. The high dimensionality of genetic data introduces a problem...
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