Article
Dopamine pathway gene variants may modulate cognitive performance in the DHS - Mind Study.
Brain and behavior - 1 Apr 2016
Martelle Susan E, Raffield Laura M, Palmer Nichole D, Cox Amanda J, Freedman Barry I, Hugenschmidt Christina E, Williamson Jeff D, Bowden Don W
Abstract excerpt
BACKGROUND: There is an established association between type 2 diabetes and accelerated cognitive decline. The exact mechanism linking type 2 diabetes and reduced cognitive function is less clear. The monoamine system, which is extensively involved in cognition, can be altered by type 2 diabetes status. Thus, this study hypothesized that sequence variants in genes linked to dopamine metabolism and associated...
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