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Article

Multiplexed direct genomic selection (MDiGS): a pooled BAC capture approach for highly accurate CNV and SNP/INDEL detection.

Nucleic acids research - 1 Jun 2014

Alvarado David M, Yang Ping, Druley Todd E, Lovett Michael, Gurnett Christina A

Abstract excerpt

Despite declining sequencing costs, few methods are available for cost-effective single-nucleotide polymorphism (SNP), insertion/deletion (INDEL) and copy number variation (CNV) discovery in a single assay. Commercially available methods require a high investment to a specific region and are only cost-effective for large samples. Here, we introduce a novel, flexible approach for multiplexed targeted sequencing...

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Topics

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Share to Chromosomes, Artificial, Bacterial
Share to DNA Copy Number Variations

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genomics

Share to INDEL Mutation

Share to Polymorphism, Single Nucleotide

Share to Sequence Analysis, DNA

Source

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Identifiers

PMID: 24682816
DOI: 10.1093/nar/gku218
PMCID: PMC4041413

Genes

HOXC11
PITX1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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