Article
p53 protein expression independently predicts outcome in patients with lower-risk myelodysplastic syndromes with del(5q).
Haematologica - 1 Jun 2014
Saft Leonie, Karimi Mohsen, Ghaderi Mehran, Matolcsy András, Mufti Ghulam J, Kulasekararaj Austin, Göhring Gudrun, Giagounidis Aristoteles, Selleslag Dominik, Muus Petra, Sanz Guillermo, Mittelman Moshe, Bowen David, Porwit Anna, Fu Tommy, Backstrom Jay, Fenaux Pierre, MacBeth Kyle J, Hellström-Lindberg Eva
Abstract excerpt
Del(5q) myelodysplastic syndromes defined by the International Prognostic Scoring System as low- or intermediate-1-risk (lower-risk) are considered to have an indolent course; however, recent data have identified a subgroup of these patients with more aggressive disease and poorer outcomes. Using deep sequencing technology, we previously demonstrated that 18% of patients with lower-risk del(5q) myelodysplastic...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.