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Article

TP53 mutation variant allele frequency is a potential predictor for clinical outcome of patients with lower-risk myelodysplastic syndromes.

Oncotarget - 14 Jun 2016

Belickova Monika, Vesela Jitka, Jonasova Anna, Pejsova Barbora, Votavova Hana, Merkerova Michaela Dostalova, Zemanova Zuzana, Brezinova Jana, Mikulenkova Dana, Lauermannova Marie, Valka Jan, Michalova Kyra, Neuwirtova Radana, Cermak Jaroslav

Abstract excerpt

TP53 mutations are frequently detected in patients with higher-risk myelodysplastic syndromes (MDS); however, the clinical impact of these mutations on the disease course of patients with lower-risk MDS is unclear. In this study of 154 lower-risk MDS patients, TP53 mutations were identified in 13% of patients, with prevalence in patients with del(5q) (23.6%) compared to non-del(5q) (3.8%). Two-thirds of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27167113
DOI: 10.18632/oncotarget.9200
PMCID: PMC5094999

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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