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Article

High-content screening of yeast mutant libraries by shotgun lipidomics.

Molecular bioSystems - 1 Jun 2014

Tarasov Kirill, Stefanko Adam, Casanovas Albert, Surma Michal A, Berzina Zane, Hannibal-Bach Hans Kristian, Ekroos Kim, Ejsing Christer S

Abstract excerpt

To identify proteins with a functional role in lipid metabolism and homeostasis we designed a high-throughput platform for high-content lipidomic screening of yeast mutant libraries. To this end, we combined culturing and lipid extraction in 96-well format, automated direct infusion nanoelectrospray ionization, high-resolution Orbitrap mass spectrometry, and a dedicated data processing framework to support lipid...

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PMID: 24681539
DOI: 10.1039/c3mb70599d

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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