Article
Polymorphism of circadian clock genes and temperamental dimensions of the TEMPS-A in bipolar disorder.
Journal of affective disorders - 1 Apr 2014
Rybakowski Janusz K, Dmitrzak-Weglarz Monika, Dembinska-Krajewska Daria, Hauser Joanna, Akiskal Karen K, Akiskal Hagop H
Abstract excerpt
BACKGROUND: Previously, we found correlations between lithium efficacy in bipolar disorder and temperamental dimensions of the TEMPS-A and also genes involved in the regulation of biological rhythms ("clock" genes). Here, were attempted to investigate an association between multiple, single nucleotide polymorphisms (SNPs) of four clock genes (CLOCK, ARNTL, TIM, PER3) and temperamental dimensions of the TEMPS-A,...
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