Article
Interleukin-7 receptor-α gene mutations are not detected in adult T-cell acute lymphoblastic leukemia.
Cancer medicine - 1 Jun 2014
Rozovski Uri, Li Ping, Harris David, Ohanian Maro, Kantarjian Hagop, Estrov Zeev
Abstract excerpt
Somatic mutations in cancer cell genes are classified according to their functional significance. Those that provide the malignant cells with significant advantage are collectively referred to as driver mutations and those that do not, are the passenger mutations. Accordingly, analytical criteria to distinguish driver mutations from passenger mutations have been recently suggested. Recent studies revealed...
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