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Article

Transphosphorylation of EGFR at Y845 plays an important role in its autophosphorylation and kinase activity.

Oncology reports - 1 May 2014

Song Hui, Huang Lei, Zhang Ming, Wang Xiuwei, Song Shuang, Yang Lin

Abstract excerpt

Epidermal growth factor receptor (EGFR) plays a critical role in various types of human cancer such as lung, breast, brain and colon cancer. However, how EGFR activation is initiated and what type of interaction is linked to its transphosphorylation and autophosphorylation as well as the biologic...

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Source

Identifiers

PMID: 24677053
DOI: 10.3892/or.2014.3102

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24677053-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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