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Article

Altered expression of transmembrane mucins, MUC1 and MUC4, in bladder cancer: pathological implications in diagnosis.

PloS one - 1 Jan 2014

Kaur Sukhwinder, Momi Navneet, Chakraborty Subhankar, Wagner David G, Horn Adam J, Lele Subodh M, Theodorescu Dan, Batra Surinder K

Abstract excerpt

PURPOSE: Radical changes in both expression and glycosylation pattern of transmembrane mucins have been observed in various malignancies. We and others have shown that MUC1 and MUC4, two transmembrane mucins, play a sentinel role in cell signaling events that drive several epithelial malignancies. In the present study, we investigated the expression profile of MUC1 and MUC4 in the non-neoplastic bladder...

Topics

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Cell Membrane
Disease Progression
Mucin-1
Neoplasm Grading
Neoplasm Invasiveness

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neoplasm Metastasis

Urinary Bladder Neoplasms

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Open in PubMed Open full text

Identifiers

PMID: 24671186
DOI: 10.1371/journal.pone.0092742
PMCID: PMC3966814

Genes

MUC1
MUC4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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