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Article

Focal sclerosis of semicircular canals with severe DFNA9 hearing impairment caused by a P51S COCH-mutation: is there a link?

Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology - 1 Jul 2014

de Varebeke Sebastien Pierre Janssens, Termote Bruno, Van Camp Guy, Govaerts Paul J, Schepers Steven, Cox Tony, Deben Kristof, Ketelslagers Katrien, Souverijns Geert

Abstract excerpt

HYPOTHESIS: Focal sclerosis of one or more semicircular canals on computed tomographic (CT) scans and a corresponding signal loss on magnetic resonance (MR) imaging are radiologic lesions that are linked to patients who are suffering from advanced otovestibular impairment caused by hereditary DFNA9 hearing loss. BACKGROUND: DFNA9 is a hereditary hearing loss that is characterized by late-onset progressive...

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Identifiers

PMID: 24662630
DOI: 10.1097/MAO.0000000000000283

Genes

COCH

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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