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Article

Hereditary Otovestibular Dysfunction and M??ni??re's Disease in a Large Belgian Family Is Caused by a Missense Mutation in the COCH Gene

1 Nov 2001

Abstract excerpt

OBJECTIVE: To report the clinical, auditory, and vestibular characteristics of a nonsyndromic otovestibular dysfunction in a large Belgian family caused by a missense mutation of the DFNA9 gene: COCH. STUDY DESIGN: Retrospective study of the clinical, audiologic, and vestibular data of 60 genetically affected cases. SETTING: Tertiary referral center. PATIENTS: All members of a Belgian kindred who carry the...

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Identifiers

PMID: 11698812
DOI: 10.1097/00129492-200111000-00028

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Hereditary Otovestibular Dysfunction and M??ni??re's Disease in a Large Belgian Family Is Caused by a Missense Mutation in the COCH GenePMID 11698812Read ↗

Audiometric, vestibular, and genetic aspects of a DFNA9 family with a G88E COCH mutation.Semantic proximity Read ↗

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Genotype-Phenotype Correlation Study in a Large Series of Patients Carrying the p.Pro51Ser (p.P51S) Variant in COCH (DFNA9) Part II: A Prospective Cross-Sectional Study of the Vestibular Phenotype in 111 Carriers.Semantic proximity Read ↗

Genotype-Phenotype Correlations of Pathogenic COCH Variants in DFNA9: A HuGE Systematic Review and Audiometric Meta-Analysis.Semantic proximity Read ↗

A common ancestor for COCH related cochleovestibular (DFNA9) patients in Belgium and The Netherlands bearing the P51S mutationSemantic proximity Read ↗

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Bi-allelic inactivating variants in the COCH gene cause autosomal recessive prelingual hearing impairment.Semantic proximity Read ↗

Mutations in the COCH gene are a frequent cause of autosomal dominant progressive cochleo-vestibular dysfunction, but not of Meniere's disease.Semantic proximity Read ↗

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