Article
Pathophysiologic phenotyping of idiopathic sudden sensorineural hearing loss: toward precision management.
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery - 1 Aug 2026
Ibrahim Iman, Rashidy Reham El, Sweet Robert, Talib Hussain
Abstract excerpt
PURPOSE: Idiopathic sudden sensorineural hearing loss (ISSNHL) is traditionally managed as a uniform clinical emergency using empirical corticosteroid protocols, yet outcomes vary widely, suggesting underlying etiologic heterogeneity. This review aims to propose a precision medicine framework for ISSNHL by re-examining the condition through specific pathophysiologic determinants, including structural third window...
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