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Article

The novelty-seeking phenotype modulates the long-lasting effects of intermittent ethanol administration during adolescence.

PloS one - 1 Jan 2014

Montagud-Romero Sandra, Daza-Losada Manuel, Vidal-Infer Antonio, Maldonado Concepción, Aguilar María A, Miñarro Jose, Rodríguez-Arias Marta

Abstract excerpt

The aim of the present study was to investigate if a novelty-seeking phenotype mediates the long-lasting consequences of intermittent EtOH intoxication during adolescence. The hole board test was employed to classify adolescent mice as High- or Low-Novelty Seekers. Subsequently, animals were administered ethanol (1.25 or 2.5 g/kg) on two consecutive days at 48-h intervals over a 14-day period. Anxiety...

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Source

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Identifiers

PMID: 24658541
DOI: 10.1371/journal.pone.0092576
PMCID: PMC3962422

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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