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Article

Bilirubin uridine diphosphate-glucuronosyltransferase variation is a genetic basis of breast milk jaundice.

The Journal of pediatrics - 1 Jul 2014

Maruo Yoshihiro, Morioka Yoriko, Fujito Hiroshi, Nakahara Sayuri, Yanagi Takahide, Matsui Katsuyuki, Mori Asami, Sato Hiroshi, Tukey Robert H, Takeuchi Yoshihiro

Abstract excerpt

OBJECTIVE: To evaluate the role of bilirubin UDP-glucuronosyltransferase family 1, polypeptide A1 (UGT1A1) gene variations on prolonged unconjugated hyperbilirubinemia associated with breast milk feeding (breast milk jaundice [BMJ]). STUDY DESIGN: UGT1A1 gene allelic variation was analyzed in 170 Japanese infants with BMJ with polymerase chain reaction-direct sequencing, and their genotypes compared with serum...

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Identifiers

PMID: 24650397
DOI: 10.1016/j.jpeds.2014.01.060
PMCID: PMC4123958

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