Article
Complex multifactorial nature of significant hyperbilirubinemia in neonates.
Pediatrics - 1 Nov 2009
Watchko Jon F, Lin Zhili, Clark Reese H, Kelleher Amy S, Walker M Whit, Spitzer Alan R
Abstract excerpt
OBJECTIVE: To determine whether glucose-6-phosphate dehydrogenase (G6PD), uridine-diphosphoglucuronosyltransferase 1A1 (UGT1A1), and hepatic solute carrier organic anion transporter 1B1 (SLCO1B1) gene variants occur at greater frequency in neonates with significant hyperbilirubinemia. METHODS: Infants with gestational ages of >or=37 weeks and ages of <7 days were studied. Case subjects had >or=1 bilirubin level...
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