Article
Transcriptome analysis reveals differential splicing events in IPF lung tissue.
PloS one - 1 Jan 2014
Nance Tracy, Smith Kevin S, Anaya Vanessa, Richardson Rhea, Ho Lawrence, Pala Mauro, Mostafavi Sara, Battle Alexis, Feghali-Bostwick Carol, Rosen Glenn, Montgomery Stephen B
Abstract excerpt
Idiopathic pulmonary fibrosis (IPF) is a complex disease in which a multitude of proteins and networks are disrupted. Interrogation of the transcriptome through RNA sequencing (RNA-Seq) enables the determination of genes whose differential expression is most significant in IPF, as well as the detection of alternative splicing events which are not easily observed with traditional microarray experiments. We...
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