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Article

Transcriptomic and Epigenetic Profiling of Fibroblasts in Idiopathic Pulmonary Fibrosis.

American journal of respiratory cell and molecular biology - 1 Jan 2022

Hanmandlu Ankit, Zhu Lisha, Mertens Tinne C J, Collum Scott, Bi Weizhen, Xiong Feng, Wang Ruoyu, Amirthalingam Rajarajan T, Ren Dewei, Han Leng, Jyothula Soma S S K, Li Wenbo, Zheng W Jim, Karmouty-Quintana Harry

Abstract excerpt

Idiopathic pulmonary fibrosis (IPF), a devastating, fibroproliferative, chronic lung disorder, is associated with expansion of fibroblasts/myofibroblasts, which leads to excessive production and deposition of extracellular matrix. IPF is typically clinically identified as end-stage lung disease, after fibrotic processes are well-established and advanced. Fibroblasts have been shown to be critically important in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34370624
DOI: 10.1165/rcmb.2020-0437OC
PMCID: PMC8803355

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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