Article
Association between H-RAS T81C genetic polymorphism and gastrointestinal cancer risk: a population based case-control study in China.
BMC cancer - 10 Sept 2008
Zhang Yongjing, Jin Mingjuan, Liu Bing, Ma Xinyuan, Yao Kaiyan, Li Qilong, Chen Kun
Abstract excerpt
BACKGROUND: Gastrointestinal cancer, such as gastric, colon and rectal cancer, is a major medical and economic burden worldwide. However, the exact mechanism of gastrointestinal cancer development still remains unclear. RAS genes have been elucidated as major participants in the development and progression of a series of human tumours and the single nucleotide polymorphism at H-RAS cDNA position 81 was...
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