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Article

Human genetic variation within neural crest enhancers: molecular and phenotypic implications.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 1 Jan 2013

Rada-Iglesias Alvaro, Prescott Sara L, Wysocka Joanna

Abstract excerpt

Developmental gene expression programmes are coordinated by the specialized distal cis-regulatory elements called enhancers, which integrate lineage- and signalling-dependent inputs to guide morphogenesis. In previous work, we characterized the genome-wide repertoire of active enhancers in human neural crest cells (hNCC), an embryonic cell population with critical roles in craniofacial development. We showed that...

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Share to Chromatin Assembly and Disassembly
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 23650634
DOI: 10.1098/rstb.2012.0360
PMCID: PMC3682725

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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