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Article

Improved linkage analysis of Quantitative Trait Loci using bulk segregants unveils a novel determinant of high ethanol tolerance in yeast.

BMC genomics - 19 Mar 2014

Duitama Jorge, Sánchez-Rodríguez Aminael, Goovaerts Annelies, Pulido-Tamayo Sergio, Hubmann Georg, Foulquié-Moreno María R, Thevelein Johan M, Verstrepen Kevin J, Marchal Kathleen

Abstract excerpt

BACKGROUND: Bulk segregant analysis (BSA) coupled to high throughput sequencing is a powerful method to map genomic regions related with phenotypes of interest. It relies on crossing two parents, one inferior and one superior for a trait of interest. Segregants displaying the trait of the superior parent are pooled, the DNA extracted and sequenced. Genomic regions linked to the trait of interest are identified by...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 24640961
DOI: 10.1186/1471-2164-15-207
PMCID: PMC4003806

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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