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Article

MLK3 promotes melanoma proliferation and invasion and is a target of microRNA-125b

18 Mar 2014

Abstract excerpt

BACKGROUND: Metastatic melanoma is a disease with high mortality and limited therapeutic options. MicroRNAs (miRNAs) can be used to classify melanoma stage. METHODS: Expression of the miRNA miR-125b and serine/threonine kinase mixed lineage kinase (MLK)3 was assessed in primary malignant melanoma tissues and several melanoma cell lines by quantitative reverse transcription PCR. The effect of MLK3 and miR-125b on...

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Share to Cutaneous Melanoma Detection and Management
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PMID: 24635082
DOI: 10.1111/ced.12286

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