Article
Carbapenem-resistant Klebsiella pneumoniae exhibit variability in capsular polysaccharide and capsule associated virulence traits.
The Journal of infectious diseases - 1 Sept 2014
Diago-Navarro Elizabeth, Chen Liang, Passet Virginie, Burack Seth, Ulacia-Hernando Amaia, Kodiyanplakkal Rosy Priya, Levi Michael H, Brisse Sylvain, Kreiswirth Barry N, Fries Bettina C
Abstract excerpt
BACKGROUND: Novel therapies are urgently needed to treat carbapenem-resistant Klebsiella pneumoniae (CR-Kp)-mediated infection, which constitute a major health threat in the United States. In order to assess if it is feasible to develop anticapsular antibodies as a potential novel therapy, it is...
Topics
- Aged
- Aged, 80 and over
- Animals
- Anti-Bacterial Agents
- Antibodies, Bacterial
- Bacterial Capsules
- Biofilms
- Blood Bactericidal Activity
- Carbapenems
- Female
- Genotype
- Humans
- Klebsiella Infections
- Klebsiella pneumoniae