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Article

Serum Antibody Responses against Carbapenem-Resistant Klebsiella pneumoniae in Infected Patients.

mSphere - 3 Mar 2021

Banerjee Kasturi, Motley Michael P, Diago-Navarro Elizabeth, Fries Bettina C

Abstract excerpt

Capsular polysaccharide (CPS) heterogeneity within carbapenem-resistant Klebsiella pneumoniae (CR-Kp) strain sequence type 258 (ST258) must be considered when developing CPS-based vaccines. Here, we sought to characterize CPS-specific antibody responses elicited by CR-Kp-infected patients. Plasma and bacterial isolates were collected from 33 hospital patients with positive CR-Kp cultures. Isolate capsules were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33658281
DOI: 10.1128/mSphere.01335-20
PMCID: PMC8546725

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