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Article

Deregulated cell death and lymphocyte homeostasis cause premature lethality in mice lacking the BH3-only proteins Bim and Bmf.

Blood - 24 Apr 2014

Labi Verena, Woess Claudia, Tuzlak Selma, Erlacher Miriam, Bouillet Philippe, Strasser Andreas, Tzankov Alexandar, Villunger Andreas

Abstract excerpt

BH3 domain-only proteins (BH3-only) proteins are members of the Bcl-2 family that play crucial roles in embryogenesis and the maintenance of tissue homeostasis by triggering apoptotic cell death. The BH3-only protein Bim is critical for developmental apoptosis of lymphocytes, securing establishment of tolerance and for the termination of immune responses. Bim is believed to act in concert with other BH3-only...

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Identifiers

PMID: 24632712
DOI: 10.1182/blood-2013-11-537217
PMCID: PMC3999752

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Deregulated cell death and lymphocyte homeostasis cause premature lethality in mice lacking the BH3-only proteins Bim and Bmf.PMID 24632712Read ↗

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