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Article

Genome-wide analysis in German shepherd dogs reveals association of a locus on CFA 27 with atopic dermatitis.

PLoS genetics - 1 May 2013

Tengvall Katarina, Kierczak Marcin, Bergvall Kerstin, Olsson Mia, Frankowiack Marcel, Farias Fabiana H G, Pielberg Gerli, Carlborg Örjan, Leeb Tosso, Andersson Göran, Hammarström Lennart, Hedhammar Åke, Lindblad-Toh Kerstin

Abstract excerpt

Humans and dogs are both affected by the allergic skin disease atopic dermatitis (AD), caused by an interaction between genetic and environmental factors. The German shepherd dog (GSD) is a high-risk breed for canine AD (CAD). In this study, we used a Swedish cohort of GSDs as a model for human AD. Serum IgA levels are known to be lower in GSDs compared to other breeds. We detected significantly lower IgA levels...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23671420
DOI: 10.1371/journal.pgen.1003475
PMCID: PMC3649999

Genes

CAD
PKP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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