Article
HBV genotype C strains with spontaneous YMDD mutations may be a risk factor for hepatocellular carcinoma.
Journal of medical virology - 1 Jun 2014
Yang Jiahong, Chen Xuebing, Zhang Hao, Chen Gao
Abstract excerpt
HBV has a relatively high mutation rate in its genome and most of these mutations are associated with the curative effect of nucleoside analogs. In this study, 1,424 patients with HBV-related liver diseases not treated with antiviral drugs, including 197 asymptomatic HBV carriers, 769 chronic hepatitis B patients, 145 acute-on-chronic liver failure (ACLF) patients, 187 HBV-related liver cirrhosis patients, and...
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