Article
The natural YMDD mutations of hepatitis B virus in Western China.
Scandinavian journal of infectious diseases - 1 Jan 2012
Zhao Jinrong, Guo Yanhai, Yan Zhen, Liang Ping, Zhang Ju, Liu Yonglan
Abstract excerpt
BACKGROUND: To provide a scientific basis for clinical genetic diagnosis before lamivudine treatment in hepatitis B virus (HBV) patients, the rate of natural YMDD mutations in Western China and the correlations between YMDD mutations and several factors were investigated in this study. METHODS: A pyrosequencing approach for detecting YMDD mutations was first developed. The sensitivity of the pyrosequencing...
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